Curis’ CA-4948 is a first-in-class IRAK4 inhibitor that is in clinical development for AML/MDS and NHL. It’s estimated that over 50% of AML patients have the IRAK4-L isoform, providing a nice patient population that could be eligible for this therapy. The company provided a recent update in anticipation of the European Hematology Association meeting in early June. They showed 8 out of 9 patients receiving some benefit from the treatment with 4 patients having a strong response (CR or CRi).
In this video, I go through the company’s clinical programs and evaluate what we can look forward to next. I also touch on $ANVS and $SIOX.
Presentation slides: https://drive.google.com/drive/folders/1MENe3kFzFosR6-ALPoY9ovpXXcERH_j3?usp=sharing
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